BDBM190841 US9181236, 81e

SMILES CC1(CC1)C(=O)Nc1ccc(F)c(c1)[C@]1(C)CS(=O)(=O)[C@]2(CCOC2)C(=N)N1

InChI Key InChIKey=VUDHVLDMTCOZNK-OALUTQOASA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 190841   

TargetBeta-secretase 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM190841(US9181236, 81e)
Affinity DataKi:  998nM ΔG°:  -8.32kcal/molepH: 5.0 T: 2°CAssay Description:A homogeneous time-resolved FRET assay can be used to determine IC50 values for inhibitors of the soluble human BACE1 catalytic domain. This assay mo...More data for this Ligand-Target Pair
In DepthDetails US Patent