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BDBM191272 US9181272, 42

SMILES: NC(=O)N1CCCc2cc(cnc12)-c1cncc(CO)c1

InChI Key: InChIKey=KZNDBPRPKAMVJP-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 191272   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Aldosterone Synthase (CYP11B2)


(Cercopithecus sabaeus)
BDBM191272
PNG
(US9181272, 42)
Show SMILES NC(=O)N1CCCc2cc(cnc12)-c1cncc(CO)c1
Show InChI InChI=1S/C15H16N4O2/c16-15(21)19-3-1-2-11-5-13(8-18-14(11)19)12-4-10(9-20)6-17-7-12/h4-8,20H,1-3,9H2,(H2,16,21)
MMDB

UniProtKB/TrEMBL

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem

Similars

US Patent
n/an/a 9.20n/an/an/an/a7.4n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
The aldosterone synthase inhibition assay employs cynomolgus adrenal gland mitochondria as the source of aldosterone synthase (CYP11B2). Mitochondr...


US Patent US9181272 (2015)


BindingDB Entry DOI: 10.7270/Q2VX0F93
More data for this
Ligand-Target Pair