BDBM191488 US9181272, 258::US9181272, 270::US9181272, 271
SMILES CN1C(CCC1=O)c1cncc(c1)-c1cnc2N(CCCc2c1)C(N)=O
InChI Key InChIKey=NKCOXVQAYLNLLJ-UHFFFAOYSA-N
Data 3 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 191488
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 52.7nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 105nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair
TargetCytochrome P450 family 11 subfamily B member 2(Cercopithecus sabaeus)
Boehringer Ingelheim International
US Patent
Boehringer Ingelheim International
US Patent
Affinity DataIC50: 16.6nMpH: 7.4Assay Description:The aldosterone synthase inhibition assay employs cynomolgus adrenal
gland mitochondria as the source of aldosterone synthase (CYP11B2).
Mitochondr...More data for this Ligand-Target Pair