BindingDB PrimarySearch

BDBM19149 CHEMBL98::N-hydroxy-N'-phenyloctanediamide::SAHA::US10011611, SAHA::US10188756, Compound SAHA::US11207431, SAHA::US11505523, Compound SAHA::US20240327418, Example SAHA::US9115116, SAHA::US9353061, SAHA::US9428447, SAHA::US9695181, Vorinostat::Vorinostat::Zolinza::cid_5311::suberoylanilide hydroxamic acid

SMILES: c1ccc(cc1)NC(=O)CCCCCCC(=O)NO

InChI Key: InChIKey=WAEXFXRVDQXREF-UHFFFAOYSA-N

Data: 64 KI 1766 IC50 12 Kd 15 EC50 2 Other 2 ITC

PDB links: 17 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2062 hits for monomerid = 19149
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Histone deacetylase 1/11/4/6/8 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 8 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 1 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	0.230	n/a	n/a	n/a	n/a	n/a	20
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Histone deacetylase 1 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 2 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 3 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 4 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 5 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	8.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 6 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 7 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 8 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 9 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 6 (Mouse)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	196	n/a	n/a	n/a	n/a	8.0	37
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Histone deacetylase 1 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	775	n/a	n/a	n/a	n/a	8.0	37
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Histone deacetylase 1 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	68	n/a	n/a	n/a	n/a	7.5	25
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Histone deacetylase 2 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	164	n/a	n/a	n/a	n/a	7.5	25
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Histone deacetylase 3 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 8 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 6 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 1 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	30	n/a	n/a	n/a	n/a	8.0	37
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Histone deacetylase 2 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	82	n/a	n/a	n/a	n/a	8.0	37
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Histone deacetylase 3 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	57	n/a	n/a	n/a	n/a	8.0	37
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Histone deacetylase 4 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	8.0	37
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Histone deacetylase 8 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.70E+3	n/a	n/a	n/a	n/a	8.0	37
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Histone deacetylase 4 [653-1084,H976Y] (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	540	n/a	n/a	n/a	n/a	n/a	25
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Histone deacetylase 6 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	25
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Histone deacetylase 5 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	25
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Histone deacetylase 7 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	25
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Histone deacetylase 1 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	30	n/a	n/a	n/a	n/a	8.0	37
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Histone deacetylase 3 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	57	n/a	n/a	n/a	n/a	8.0	37
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Histone deacetylase 4 [653-1084,H976Y] (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	540	n/a	n/a	n/a	n/a	7.5	37
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Histone deacetylase 4 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a	25
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Histone deacetylase 6 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	25
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Lysine-specific demethylase 4E (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	5.40E+5	n/a	n/a	n/a	n/a	7.5	37
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Histone deacetylase 1 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	65	n/a	n/a	n/a	n/a	8.0	37
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Histone deacetylase 8 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.86E+3	n/a	n/a	n/a	n/a	n/a	25
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Histone deacetylase (Plasmodium falciparum (isolate 3D7))	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	59	n/a	n/a	n/a	n/a	7.5	23
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Histone deacetylase 1 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	293	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 2 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	683	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 3/Nuclear receptor corepressor 2 [395-489] (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	435	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 4 [627-1085] (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 5 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 6 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	17.7	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 7 [518-592] (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 8 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 9 [604-1066] (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Polyamine deacetylase HDAC10 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	604	n/a	n/a	n/a	n/a	n/a	n/a
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Histone deacetylase 11 (Human)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	597	n/a	n/a	n/a	n/a	n/a	n/a
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Zinc finger protein GLI1 (Mouse)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	2.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Protein Wnt-3a (Mouse)	BDBM19149 (Zolinza \| suberoylanilide hydroxamic acid \| CHEMBL...) Show SMILES Show InChI	GoogleScholar	UniChem	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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