BDBM191596 6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5-a]pyrimidine-3-carbonitrile (N8)

SMILES: CC1=C(C(=O)n2c(c(cn2)C#N)N1)C(C)C

InChI Key: InChIKey=UHVUUCAAVHIPKM-UHFFFAOYSA-N

Data: 13 IC50  2 Kd

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 191596   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 5A [1-739] (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	25
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Lysine-specific demethylase 5B [1-755] (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	25
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Lysine-specific demethylase 5C [1-789] (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	25
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Lysine-specific demethylase 5D [1-760] (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.00E+3	n/a	n/a	n/a	n/a	n/a	25
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Lysine-specific demethylase 5B [1-755] (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	400	n/a	n/a	n/a	n/a	n/a	25
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Lysine-specific demethylase 5C [1-789] (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+3	n/a	n/a	n/a	n/a	n/a	25
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Lysine-specific demethylase 5A [1-588] (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 5B [1-604] (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 5A [1-1090] (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	490	n/a	n/a	n/a	n/a	7.2	25
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					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	7.2	25
TBA									Citation and Details
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Lysine-specific demethylase 5C (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a	7.2	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Human)	BDBM191596 (6-isopropyl-5-methyl-7-oxo-4,7-dihydropyrazolo[1,5...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair