BDBM191600 2-(5-((4-chloro-2-methylbenzyl)oxy)-1Hpyrazol-1-yl)isonicotinic acid (N19)::US10173996, Example 89::US20240139197, Compound 33::US9604961, Example 89::US9714230, 89::US9908865, Example 89

SMILES: Cc1cc(Cl)ccc1COc1ccnn1-c1cc(ccn1)C(O)=O

InChI Key: InChIKey=PSOBPHXKKHPWMU-UHFFFAOYSA-N

Data: 36 IC50  2 Kd  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 39 hits for monomerid = 191600   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 5B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 4A (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	99	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 4E (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 2A (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	820	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 6B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 4C (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	35	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 4B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific histone demethylase 1A (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 4D (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 3A (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5D [1-760] (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	41	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A [1-739] (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B [1-755] (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C [1-789] (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A [1-588] (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B [1-604] (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A [1-1090] (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	240	n/a	n/a	n/a	n/a	7.2	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	175	n/a	n/a	n/a	n/a	7.2	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	800	n/a	n/a	n/a	n/a	7.2	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5A/5B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 2B (Human)	BDBM191600 (US9714230, 89 | 2-(5-((4-chloro-2-methylbenzyl)oxy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
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