BDBM191652 US9186360, 51::US9186360, 52

SMILES Cn1c2scc(CC(=O)Nc3nc(cs3)-c3ccc(F)c(c3F)C(F)(F)F)c2c(=O)n(C)c1=O

InChI Key InChIKey=XOPMVFNBFICPDB-UHFFFAOYSA-N

Data  10 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 191652   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 51 | US9186360, 52)
Affinity DataIC50:  4.84nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 51 | US9186360, 52)
Affinity DataIC50:  2.49nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 51 | US9186360, 52)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 51 | US9186360, 52)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 51 | US9186360, 52)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 51 | US9186360, 52)
Affinity DataIC50:  2.52E+3nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 51 | US9186360, 52)
Affinity DataIC50:  4.57E+3nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 51 | US9186360, 52)
Affinity DataIC50:  3.04E+3nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 51 | US9186360, 52)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191652(US9186360, 51 | US9186360, 52)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent