BDBM191725 US9186360, 76

SMILES Cc1oc2n(C)c(=O)n(C)c(=O)c2c1CC(=O)Nc1nc(cs1)-c1ccc(c(F)c1F)C(F)(F)F

InChI Key InChIKey=MQPVCEGYFVTWDL-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 191725   

TargetTransient receptor potential cation channel subfamily A member 1(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191725(US9186360, 76)
Affinity DataIC50:  4.02nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191725(US9186360, 76)
Affinity DataIC50:  8.01E+3nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily M member 8(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191725(US9186360, 76)
Affinity DataIC50: >1.00E+4nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 4(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191725(US9186360, 76)
Affinity DataIC50:  8.92E+3nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 3(Homo sapiens (Human))
Glenmark Pharmaceuticals

US Patent
LigandPNGBDBM191725(US9186360, 76)
Affinity DataIC50:  2.50E+3nMT: 2°CAssay Description:The inhibition of TRPA1 receptor activation was measured as inhibition of allylisothiocyanate (AITC) induced cellular uptake of radioactive calcium. ...More data for this Ligand-Target Pair
In DepthDetails US Patent