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BDBM192507 US9187477, 3

SMILES: O[C@@H]1COC2[C@@H](COC12)Oc1nc2cc(Cl)c(nc2[nH]1)-c1ccc(cc1)[C@@H]1CC[C@@H](CC1)NC(=O)OC1CCCC1

InChI Key: InChIKey=NWACPWAYWSNEHT-VAYFKCEKSA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 192507   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5'-AMP-activated protein kinase catalytic subunit alpha-1


(Homo sapiens (Human))
BDBM192507
PNG
(US9187477, 3)
Show SMILES O[C@@H]1COC2[C@@H](COC12)Oc1nc2cc(Cl)c(nc2[nH]1)-c1ccc(cc1)[C@@H]1CC[C@@H](CC1)NC(=O)OC1CCCC1
Show InChI InChI=1S/C30H35ClN4O6/c31-21-13-22-28(35-29(33-22)41-24-15-39-26-23(36)14-38-27(24)26)34-25(21)18-7-5-16(6-8-18)17-9-11-19(12-10-17)32-30(37)40-20-3-1-2-4-20/h5-8,13,17,19-20,23-24,26-27,36H,1-4,9-12,14-15H2,(H,32,37)(H,33,34,35)/t17-,19+,23-,24-,26?,27?/m1/s1
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem

Similars

US Patent
n/an/an/an/a 108n/an/a7.0n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Activated AMPK complex 1 (containing alphal betalgammal ) was obtained from baculovirus expression system. The gene encoding AMPK alphal was cloned i...


US Patent US9187477 (2015)


BindingDB Entry DOI: 10.7270/Q2CR5S58
More data for this
Ligand-Target Pair