BDBM193081 US9193726, 69

SMILES: C[C@@H]([C@@H]1CC[C@@H](O1)c1cc(F)c(Cl)cc1C(F)(F)F)N1CCn2c(ccc(-n3cnc(C)c3)c2=O)C1=O

InChI Key: InChIKey=AKCDDYGYIGPEKL-UHFFFAOYSA-N

Data: 6 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 193081   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Presenilin-1 (Human)	BDBM193081 (US9193726, 69) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.84	n/a	n/a	n/a	n/a	n/a	37
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Presenilin-1 (Human)	BDBM193081 (US9193726, 69) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Presenilin-1 (Human)	BDBM193081 (US9193726, 69) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
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Presenilin-1 (Human)	BDBM193081 (US9193726, 69) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
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Beta-secretase 1 (Human)	BDBM193081 (US9193726, 69) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Cathepsin D (Human)	BDBM193081 (US9193726, 69) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Trypsin (Human)	BDBM193081 (US9193726, 69) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Neurogenic locus notch homolog protein 1 (Human)	BDBM193081 (US9193726, 69) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>1.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
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