BDBM19392 2,4-diaminopyrimidine derivative, 8h::6-[(benzyloxy)methyl]-5-[4-({[4-(trifluoromethyl)phenyl]methyl}amino)phenyl]pyrimidine-2,4-diamine

SMILES Nc1nc(N)c(c(COCc2ccccc2)n1)-c1ccc(NCc2ccc(cc2)C(F)(F)F)cc1

InChI Key InChIKey=RVCXILYFOWJXDJ-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 19392   

TargetGrowth hormone secretagogue receptor type 1(Homo sapiens (Human))
Abbott Laboratories

LigandPNGBDBM19392(2,4-diaminopyrimidine derivative, 8h | 6-[(benzylo...)
Affinity DataIC50:  2.90nM EC50:  97nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed