BDBM194145 US9200001, 61
SMILES Cc1nc(C)n(n1)-c1cc(nc(n1)C#N)[C@@H]1C[C@H]1c1nc2ccccc2n1C
InChI Key InChIKey=MDYSTXWIXMTVTI-ZIAGYGMSSA-N
Data 1 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 194145
TargetIsoform PDE10A2 of cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (PDE10A2)(Homo sapiens (Human))
Merck Sharp & Dohme
US Patent
Merck Sharp & Dohme
US Patent
Affinity DataKi: 0.0850nMAssay Description:In a typical experiment the PDE10 inhibitory activity of the compounds
of the present invention was determined in accordance with the following
exp...More data for this Ligand-Target Pair