BDBM19461 α-CA inhibitor, 5::5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1-benzopyran-4-one::CHEMBL32571::Naringenin::Naringenin (NAR)::naringetol::salipurpol

SMILES: c1cc(ccc1[C@@H]2CC(=O)c3c(cc(cc3O2)O)O)O

InChI Key: InChIKey=FTVWIRXFELQLPI-UHFFFAOYSA-N

Data: 7 KI  8 IC50  6 ITC

PDB links: 24 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 19461   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Human)	BDBM19461 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.23E+4	n/a	n/a	n/a	n/a	7.6	22
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Estrogen receptor beta (Human)	BDBM19461 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.35E+4	n/a	n/a	n/a	n/a	7.6	22
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Dipeptidyl peptidase 4 (Pig)	BDBM19461 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Urease subunit beta (Helicobacter pylori (strain ATCC 700392 / 26695) (...)	BDBM19461 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.28E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Acetylcholinesterase (Rat)	BDBM19461 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Carboxylic ester hydrolase (Rat)	BDBM19461 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Aromatase (Human)	BDBM19461 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		0.00110	n/a	1.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Carbonic anhydrase 2 (Human)	BDBM19461 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		113	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
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Carbonic anhydrase 1 (Human)	BDBM19461 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		970	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
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Carbonic anhydrase 4 (Human)	BDBM19461 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.12E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
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Carbonic anhydrase 6 (Human)	BDBM19461 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.49E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
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Carbonic anhydrase 3 (Bovine)	BDBM19461 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		2.21E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
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Aldehyde oxidase 1 (Guinea pig)	BDBM19461 (5,7-dihydroxy-2-(4-hydroxyphenyl)-3,4-dihydro-2H-1...) Show SMILES Show InChI	GoogleScholar	UniChem		1.48E+5	n/a	2.12E+5	n/a	n/a	n/a	n/a	7.0	n/a
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