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BDBM194932 US9206184, 113

SMILES: CCOCc1c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn2c1C(=O)N1CCC(CC1)C(N)=O

InChI Key: InChIKey=OJZYTLWGMXRJNU-UHFFFAOYSA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194932   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 1


(Homo sapiens (Human))
BDBM194932
PNG
(US9206184, 113)
Show SMILES CCOCc1c(-c2cc3cc(C)cc(OC)c3s2)c2c(N)ncnn2c1C(=O)N1CCC(CC1)C(N)=O
Show InChI InChI=1S/C26H30N6O4S/c1-4-36-12-17-20(19-11-16-9-14(2)10-18(35-3)23(16)37-19)22-24(27)29-13-30-32(22)21(17)26(34)31-7-5-15(6-8-31)25(28)33/h9-11,13,15H,4-8,12H2,1-3H3,(H2,28,33)(H2,27,29,30)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 52.7n/an/an/an/a7.022



Bayer Intellectual Property GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair