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BDBM194999 US9206198, 60

SMILES: CNC(CN1CCC2(CCN(C2=O)C2=C(C)C(=O)OC2)CC1)c1ccc2C(=O)OCc2c1C

InChI Key: InChIKey=RZCRSNUMKFECQU-UHFFFAOYNA-N

Data: 1 IC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 194999   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
ATP-sensitive inward rectifier potassium channel 1


(Homo sapiens (Human))
BDBM194999
PNG
(US9206198, 60)
Show SMILES CNC(CN1CCC2(CCN(C2=O)C2=C(C)C(=O)OC2)CC1)c1ccc2C(=O)OCc2c1C
Show InChI InChI=1/C25H31N3O5/c1-15-17(4-5-18-19(15)13-32-23(18)30)20(26-3)12-27-9-6-25(7-10-27)8-11-28(24(25)31)21-14-33-22(29)16(21)2/h4-5,20,26H,6-14H2,1-3H3
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KEGG

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PC cid
PC sid
UniChem
US Patent
n/an/a 100n/an/an/an/an/a37



Merck Sharp & Dohme Corp

US Patent


Assay Description
The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D...


US Patent US9206198 (2015)


BindingDB Entry DOI: 10.7270/Q2NZ86FH
More data for this
Ligand-Target Pair