BDBM195074 US9212153, 133,Ex. 98

SMILES COC1CCC2(CC1)Oc1ccc(OCC(F)(F)F)cc1C21N=C(N)N(C)C1=O

InChI Key InChIKey=UJULVWISQZDCCY-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 195074   

TargetBeta-secretase 1 [1-458](Homo sapiens (Human))
Vitae Pharmaceuticals

US Patent
LigandPNGBDBM195074(US9212153, 133,Ex. 98)
Affinity DataIC50:  38.5nMpH: 4.4Assay Description:For each compound being tested, the BACE activity was monitored in a fluorescence quenching assay (FRET) using the ectodomain of BACE (aa 1-454) fuse...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent