BDBM195612 GSK467

SMILES: c1ccc(cc1)Cn2cc(cn2)OC3=Nc4cnccc4C(=O)N3

InChI Key: InChIKey=ZTYRLXUTLYBVHH-UHFFFAOYSA-N

Data: 21 IC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 21 hits for monomerid = 195612   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Lysine-specific demethylase 4C (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 5C (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 5C (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.98E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 4C (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 4C (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 4A (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	631	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 6B (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 4D (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	398	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 5C (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
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Prolyl hydroxylase EGLN3 (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1.00E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 4E (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	501	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 5A [1-801] (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	24	n/a	n/a	n/a	n/a	7.5	n/a
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Lysine-specific demethylase 5B (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 5B (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5C (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Lysine-specific demethylase 3A (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3.39E+4	n/a	n/a	n/a	n/a	7.5	n/a
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					More data for this Ligand-Target Pair
Lysine-specific demethylase 4C (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.10E+3	n/a	n/a	n/a	n/a	7.5	n/a
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Lysine-specific demethylase 5D [1-775] (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	77	n/a	n/a	n/a	n/a	7.5	n/a
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Lysine-specific demethylase 5C [1-765] (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	65	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Lysine-specific demethylase 5B (Human)	BDBM195612 (GSK467) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	26	n/a	n/a	n/a	n/a	7.5	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair