BDBM195613 US9206173, 1

SMILES C[C@H](Nc1nc2CCN(Cc2c(=O)n1CC#C)C(=O)c1ccc(cc1F)C#N)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=ADILCYSDZPCUMZ-INIZCTEOSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 195613   

TargetProlactin-releasing peptide receptor(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM195613(US9206173, 1)
Affinity DataKi:  5nM ΔG°:  -11.3kcal/molepH: 7.4 T: 2°CAssay Description:Receptor-expressing HEK 293 cell membrane fraction was analyzed by modifying the methods of C. J. Langmead et al. (see Langmead C J, Szekeres P G; Ch...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetProlactin-releasing peptide receptor(Homo sapiens (Human))
Otsuka Pharmaceutical

US Patent
LigandPNGBDBM195613(US9206173, 1)
Affinity DataIC50:  42nMpH: 7.4 T: 2°CAssay Description:HEK293 cells expressing human GPR10 were maintained in Dulbecco's Modified Eagles' medium supplemented with 10% fetal bovine serum, 1% penici...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent