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BDBM195853 US9670212, 188 8-methyl-2-(2-methylphenyl)-3-[(9H-purin-6-ylthio)methyl]quinoline

SMILES: Cc1ccccc1-c1nc2c(C)cccc2cc1CSc1ncnc2[nH]cnc12

InChI Key: InChIKey=LRWHJZUUNFKVKD-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 195853   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform/gamma isoform


(Homo sapiens (Human))
BDBM195853
PNG
(US9670212, 188 8-methyl-2-(2-methylphenyl)-3-[(9H-...)
Show SMILES Cc1ccccc1-c1nc2c(C)cccc2cc1CSc1ncnc2[nH]cnc12
Show InChI InChI=1S/C23H19N5S/c1-14-6-3-4-9-18(14)20-17(10-16-8-5-7-15(2)19(16)28-20)11-29-23-21-22(25-12-24-21)26-13-27-23/h3-10,12-13H,11H2,1-2H3,(H,24,25,26,27)
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 150n/an/an/an/an/an/a



Exelixis Inc

US Patent


Assay Description
Kinase activity is measured as the percent of ATP consumed following the kinase reaction using luciferase-luciferin-coupled chemiluminescence. Reacti...


US Patent US9670212 (2017)


BindingDB Entry DOI: 10.7270/Q27H1GR0
More data for this
Ligand-Target Pair