BDBM196075 US9206199, 180
SMILES O=C(Cc1ccc(nc1)-n1cnnn1)N1CCN2C[C@@H](OC[C@@H]2C1)c1ccc2nonc2c1
InChI Key InChIKey=BZFLRKRZTBWDNX-QFBILLFUSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 196075
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 104nMAssay Description:Inhibition of human ROMK expressed in CHO cells after 6 mins at -70 mV holding potential by electrophysiology methodMore data for this Ligand-Target Pair
TargetATP-sensitive inward rectifier potassium channel 1(Homo sapiens (Human))
Merck Research Laboratories
Curated by ChEMBL
Merck Research Laboratories
Curated by ChEMBL
Affinity DataIC50: 590nMAssay Description:The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...More data for this Ligand-Target Pair