BDBM196613 US9670214, TABLE 16.62

SMILES FC(F)(F)Oc1ccc(Nc2cc(ncn2)-c2cnn(Cc3ccccc3)c2)cc1

InChI Key InChIKey=RUDZVRRHBGESJG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 196613   

TargetNon-specific protein-tyrosine kinase [T818I](Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM196613(US9670214, TABLE 16.62)
Affinity DataIC50:  1.30E+3nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNon-specific protein-tyrosine kinase(Homo sapiens (Human))
Dana-Farber Cancer Institute

US Patent
LigandPNGBDBM196613(US9670214, TABLE 16.62)
Affinity DataIC50:  170nMpH: 7.5Assay Description:In vitro kinase assays were carried out by using recombinant murine c-abl containing SH3, SH2 and kinase domains (residues 46-531) and full length im...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent