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BDBM196713 US9212171, 35

SMILES: CN1[C@H]2CCCC[C@H]2[C@H](C1=O)c1ccc(cn1)C#Cc1ccccc1

InChI Key: InChIKey=OFHHFXKOVBOQJU-YGPNDOBFNA-N

Data: 1 EC50

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 196713   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Metabotropic glutamate receptor 5a (mGluR5)


(Homo sapiens (Human))
BDBM196713
PNG
(US9212171, 35)
Show SMILES CN1[C@H]2CCCC[C@H]2[C@H](C1=O)c1ccc(cn1)C#Cc1ccccc1
Show InChI InChI=1/C22H22N2O/c1-24-20-10-6-5-9-18(20)21(22(24)25)19-14-13-17(15-23-19)12-11-16-7-3-2-4-8-16/h2-4,7-8,13-15,18,20-21H,5-6,9-10H2,1H3/t18-,20+,21+/s2
PDB

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/an/an/a 101n/an/an/a37



Hoffmann-La Roche Inc

US Patent


Assay Description
A monoclonal HEK-293 cell line stably transfected with a cDNA encoding for the human mGlu5a receptor was generated; for the work with mGlu5 Positive ...


US Patent US9212171 (2015)


BindingDB Entry DOI: 10.7270/Q25Q4TWH
More data for this
Ligand-Target Pair