BDBM19688 (2S)-3-cyclohexyl-1-(morpholin-4-yl)-1-oxopropan-2-yl N-[(1S)-1-cyclopropyl-2-(5-fluoro-3,3-dimethyl-2,3-dihydro-1H-indol-1-yl)ethyl]carbamate::Arylaminoethyl carbamate, 19

SMILES CC1(C)CN(C[C@@H](NC(=O)O[C@@H](CC2CCCCC2)C(=O)N2CCOCC2)C2CC2)c2ccc(F)cc12

InChI Key InChIKey=XAXXJCXWAJJGKZ-RSXGOPAZSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19688   

TargetCathepsin S(Homo sapiens (Human))
Gnf

LigandPNGBDBM19688((2S)-3-cyclohexyl-1-(morpholin-4-yl)-1-oxopropan-2...)
Affinity DataKi:  19nM ΔG°:  -10.9kcal/molepH: 5.5 T: 2°CAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProcathepsin L(Homo sapiens (Human))
Gnf

LigandPNGBDBM19688((2S)-3-cyclohexyl-1-(morpholin-4-yl)-1-oxopropan-2...)
Affinity DataKi: >3.00E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin K(Homo sapiens (Human))
Gnf

LigandPNGBDBM19688((2S)-3-cyclohexyl-1-(morpholin-4-yl)-1-oxopropan-2...)
Affinity DataKi: >3.00E+4nMAssay Description:The recombinant human cathepsin enzyme was preincubated with inhibitor for 20 minutes prior to addition of substrate. The substrate hydrolysis was mo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed