BDBM19741 2-Cyano-pyrimidine, 17f::2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{4-[(4-methylpiperazin-1-yl)methyl]phenyl}ethyl)pyrimidine-5-carboxamide

SMILES: CN1CCN(Cc2ccc(CCNC(=O)c3cnc(nc3NCC(C)(C)C)C#N)cc2)CC1

InChI Key: InChIKey=GASCFELIQZXIAB-UHFFFAOYSA-N

Data: 3 IC50

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Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 19741   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Human)	BDBM19741 (2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{4-[(4-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.0110	n/a	n/a	n/a	n/a	7.0	22
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Procathepsin L (Human)	BDBM19741 (2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{4-[(4-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.330	n/a	n/a	n/a	n/a	5.5	22
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					More data for this Ligand-Target Pair
Cathepsin S (Human)	BDBM19741 (2-cyano-4-[(2,2-dimethylpropyl)amino]-N-(2-{4-[(4-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair