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BDBM197832 US9216988, 83

SMILES: CC(=O)N1CCN(CC1)c1ccc(CN(C2CCC2)S(=O)(=O)Cc2ccc(Cl)cc2Cl)c(F)c1

InChI Key: InChIKey=FVPQCHOIKIAIJK-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197832   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma (RORC)


(Homo sapiens (Human))
BDBM197832
PNG
(US9216988, 83)
Show SMILES CC(=O)N1CCN(CC1)c1ccc(CN(C2CCC2)S(=O)(=O)Cc2ccc(Cl)cc2Cl)c(F)c1
Show InChI InChI=1S/C24H28Cl2FN3O3S/c1-17(31)28-9-11-29(12-10-28)22-8-6-18(24(27)14-22)15-30(21-3-2-4-21)34(32,33)16-19-5-7-20(25)13-23(19)26/h5-8,13-14,21H,2-4,9-12,15-16H2,1H3
PDB

UniProtKB/SwissProt
UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 15n/an/an/an/a7.4n/a



Genentech Inc

US Patent


Assay Description
On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash bu...


US Patent US9216988 (2015)


BindingDB Entry DOI: 10.7270/Q2TB15QC
More data for this
Ligand-Target Pair