BindingDB logo
myBDB logout

BDBM197841 US9216988, 104

SMILES: CC(=O)N1CCN(CC1)c1ccc(CN(C2CCC2)S(=O)(=O)c2cc(C)cc(C)c2)c(F)c1

InChI Key: InChIKey=WFGBWWIBCIBTRA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 197841   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Nuclear receptor ROR-gamma (RORC)


(Homo sapiens (Human))
BDBM197841
PNG
(US9216988, 104)
Show SMILES CC(=O)N1CCN(CC1)c1ccc(CN(C2CCC2)S(=O)(=O)c2cc(C)cc(C)c2)c(F)c1
Show InChI InChI=1S/C25H32FN3O3S/c1-18-13-19(2)15-24(14-18)33(31,32)29(22-5-4-6-22)17-21-7-8-23(16-25(21)26)28-11-9-27(10-12-28)20(3)30/h7-8,13-16,22H,4-6,9-12,17H2,1-3H3
PDB

Reactome pathway

UniProtKB/TrEMBL

GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 24n/an/an/an/a7.4n/a



Genentech Inc

US Patent


Assay Description
On day of the assay, 100 uL of 0.05% CHAPS (in deionized H2O) was added to all wells of the GFB Unifilter plate and allowed soak for 1 h. A wash bu...


US Patent US9216988 (2015)


BindingDB Entry DOI: 10.7270/Q2TB15QC
More data for this
Ligand-Target Pair