BDBM198063 US9221795, 59
SMILES Nc1nc(N)c(Cl)c(N[C@@H](C2CC2)c2nc3c(F)ccc(C#N)c3c(=O)n2-c2cccnc2)n1
InChI Key InChIKey=NHZVHHAMKTUMFU-INIZCTEOSA-N
Data 1 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 1 hit for monomerid = 198063
TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform(Homo sapiens (Human))
Gilead Sciences
US Patent
Gilead Sciences
US Patent
Affinity DataIC50: 380nMpH: 7.4Assay Description:Class I PI3K isoforms were expressed and purified as heterodimeric recombinant proteins. All assay reagents and buffers for the TR-FRET assay were pu...More data for this Ligand-Target Pair