BDBM198171 2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)methyl)-5,6-diphenyl-1,2,4-triazin-3(2H)-one (3c)

SMILES COc1ccc(Nc2nnc(Cn3nc(-c4ccccc4)c(nc3=O)-c3ccccc3)o2)cc1

InChI Key InChIKey=STOZTMZCUWJXDR-UHFFFAOYSA-N

Data  1 KI  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 198171   

TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM198171(2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...)
Affinity DataKi:  650nMAssay Description:The enzyme kinetics were determined, wherein the arachidonic acid substrate either in the absence or presence of selected derivatives were evaluated ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM198171(2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50:  770nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM198171(2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50:  900nMAssay Description:Inhibition of ovine COX-2 by colorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 2(Ovis aries (Sheep))
Indian Institute Of Technology (Banaras Hindu University)

LigandPNGBDBM198171(2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50:  600nMAssay Description:Inhibition of ovine COX2 by colorimetric assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Zagazig University

Curated by ChEMBL
LigandPNGBDBM198171(2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50:  6.00E+4nMAssay Description:Inhibition of ovine COX-1 by colorimetric analysisMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProstaglandin G/H synthase 1(Ovis aries (Sheep))
Zagazig University

Curated by ChEMBL
LigandPNGBDBM198171(2-((5-(4-Methoxyphenylamino)-1,3,4-oxadiazol-2-yl)...)
Affinity DataIC50:  6.05E+4nMAssay Description:The ability of the compounds (3c-3e and 4c-4e) to inhibit ovine COX-1 and COX-2 was evaluated using a colorimetric COX (ovine) inhibitor screening as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed