BDBM198192 (S,E)-N-hydroxy-3-(3-(N-(2-(naphthalen-1-ylamino)-2-oxo-1-phenylethyl)sulfamoyl)phenyl)acrylamide (10s)

SMILES ONC(=O)\C=C\c1cccc(c1)S(=O)(=O)N[C@H](C(=O)Nc1cccc2ccccc12)c1ccccc1

InChI Key InChIKey=JCEFNCFZXQDHRY-ZOGILVBSSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 198192   

TargetHistone deacetylase 1(Homo sapiens (Human))
Shandong University

LigandPNGBDBM198192((S,E)-N-hydroxy-3-(3-(N-(2-(naphthalen-1-ylamino)-...)
Affinity DataIC50:  93nMAssay Description:In brief, 10 μL of enzyme solution (HeLa nuclear extracts, HDAC1, HDAC4, HDAC6, HDAC8, HDAC11) was mixed with various concentrations of target c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 8(Homo sapiens (Human))
Shandong University

LigandPNGBDBM198192((S,E)-N-hydroxy-3-(3-(N-(2-(naphthalen-1-ylamino)-...)
Affinity DataIC50:  659nMAssay Description:In brief, 10 μL of enzyme solution (HeLa nuclear extracts, HDAC1, HDAC4, HDAC6, HDAC8, HDAC11) was mixed with various concentrations of target c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 11(Homo sapiens (Human))
Shandong University

LigandPNGBDBM198192((S,E)-N-hydroxy-3-(3-(N-(2-(naphthalen-1-ylamino)-...)
Affinity DataIC50:  3.85E+3nMAssay Description:In brief, 10 μL of enzyme solution (HeLa nuclear extracts, HDAC1, HDAC4, HDAC6, HDAC8, HDAC11) was mixed with various concentrations of target c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
Shandong University

LigandPNGBDBM198192((S,E)-N-hydroxy-3-(3-(N-(2-(naphthalen-1-ylamino)-...)
Affinity DataIC50:  80nMAssay Description:In brief, 10 μL of enzyme solution (HeLa nuclear extracts, HDAC1, HDAC4, HDAC6, HDAC8, HDAC11) was mixed with various concentrations of target c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetHistone deacetylase 4(Homo sapiens (Human))
Shandong University

LigandPNGBDBM198192((S,E)-N-hydroxy-3-(3-(N-(2-(naphthalen-1-ylamino)-...)
Affinity DataIC50:  2.30E+4nMAssay Description:In brief, 10 μL of enzyme solution (HeLa nuclear extracts, HDAC1, HDAC4, HDAC6, HDAC8, HDAC11) was mixed with various concentrations of target c...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed