BDBM19857 N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(morpholin-4-yl)-1,3-thiazol-4-yl]benzamide::aryl-morpholino-containing analogue, 12

SMILES: O=C(NC1(CCCCC1)C(=O)NCC#N)c1ccc(cc1)-c1csc(n1)N1CCOCC1

InChI Key: InChIKey=TYJLGELUBBAGKK-UHFFFAOYSA-N

Data: 1 KI  6 IC50  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 19857   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cathepsin K (Rabbit)	BDBM19857 (N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.30	n/a	n/a	n/a	n/a	5.5	22
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Procathepsin L (Human)	BDBM19857 (N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.40E+4	n/a	>1.00E+4	n/a	n/a	5.5	22
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Cathepsin B (Human)	BDBM19857 (N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.20E+3	n/a	2.90E+3	n/a	n/a	6.0	22
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Cathepsin S (Human)	BDBM19857 (N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.70E+4	n/a	>1.00E+4	n/a	n/a	6.5	22
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Cathepsin K (Rabbit)	BDBM19857 (N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.5	n/a	41	n/a	n/a	5.5	22
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Cathepsin S (Mouse)	BDBM19857 (N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8.50E+3	n/a	6.70E+3	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Cathepsin K (Rabbit)	BDBM19857 (N-{1-[(cyanomethyl)carbamoyl]cyclohexyl}-4-[2-(mor...) Show SMILES Show InChI	GoogleScholar	UniChem		2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair