BDBM199241 US9221808, 1am::US9221808, 1am-HCl::US9221808, 1am-Mes

SMILES COc1ccc(CNC(=O)Nc2nc(cs2)-c2ccncc2)cc1

InChI Key InChIKey=BHCICEQMPOQDHS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 199241   

TargetRho-associated protein kinase 2(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM199241(US9221808, 1am-HCl | US9221808, 1am-Mes | US922180...)
Affinity DataIC50: 7.42E+3nMAssay Description:Attention was focused on exploring, in turn, the SAR around the phenyl ring A, branching and substitution at the benzylic position, urea linkage of 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM199241(US9221808, 1am-HCl | US9221808, 1am-Mes | US922180...)
Affinity DataIC50: 9.12E+3nMAssay Description:Attention was focused on exploring, in turn, the SAR around the phenyl ring A, branching and substitution at the benzylic position, urea linkage of 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM199241(US9221808, 1am-HCl | US9221808, 1am-Mes | US922180...)
Affinity DataIC50: 1.53E+4nMAssay Description:Attention was focused on exploring, in turn, the SAR around the phenyl ring A, branching and substitution at the benzylic position, urea linkage of 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent

TargetRho-associated protein kinase 1(Human)
H. Lee Moffitt Cancer Center and Research Institute

US Patent
LigandPNGBDBM199241(US9221808, 1am-HCl | US9221808, 1am-Mes | US922180...)
Affinity DataIC50: 3.62E+4nMAssay Description:Attention was focused on exploring, in turn, the SAR around the phenyl ring A, branching and substitution at the benzylic position, urea linkage of 1...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/8/2016
Entry Details
US Patent