BDBM199250 US9221808, 1bo::US9221808, 1bo-HCl::US9221808, 1bo-Mes

SMILES: Oc1cccc(CNC(=O)Nc2nc(cs2)-c2ccncc2)c1

InChI Key: InChIKey=GDVRVPIXWXOKQO-UHFFFAOYSA-N

Data: 31 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 31 hits for monomerid = 199250   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Myotonin-protein kinase (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 2 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Rho-associated protein kinase 2 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
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Activated CDC42 kinase 1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase PAK 1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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Inhibitor of nuclear factor kappa-B kinase subunit epsilon (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase TBK1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase beta-1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase JAK2 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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Rho-associated protein kinase 2 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.450	n/a	n/a	n/a	n/a	n/a	n/a
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Aurora kinase A (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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RAC-alpha serine/threonine-protein kinase (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase N1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase MRCK alpha (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
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Casein kinase I isoform alpha (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
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Serine/threonine-protein kinase Sgk1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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Glycogen synthase kinase-3 beta (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.80	n/a	n/a	n/a	n/a	n/a	n/a
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Ribosomal protein S6 kinase alpha-1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	<1	n/a	n/a	n/a	n/a	n/a	n/a
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LIM domain kinase 1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.530	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
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Myosin light chain kinase, smooth muscle (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 2 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Rho-associated protein kinase 1 (Human)	BDBM199250 (US9221808, 1bo-HCl | US9221808, 1bo-Mes | US922180...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair