BDBM19992 2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methyl-[2,2-di(phenyl)ethyl]amino]propoxy]phenyl]acetic acid::2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]methyl}(2,2-diphenylethyl)amino)propoxy]phenyl}acetic acid::CHEMBL59030::GSK-3965::GW3965::US10543183, Compound GW3965::US10669296, Compound GW3965::US10945978, Compound 2

SMILES: c1ccc(cc1)C(C[N@](CCCOc2cccc(c2)CC(=O)O)Cc3cccc(c3Cl)C(F)(F)F)c4ccccc4

InChI Key: InChIKey=NAXSRXHZFIBFMI-UHFFFAOYSA-N

Data: 3 KI  14 IC50  1 Kd  38 EC50

PDB links: 3 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 53 hits for monomerid = 19992   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.401	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.228	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	6.97E+3	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	235	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	78	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	310	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	280	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	501	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	410	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	794	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	420	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	400	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	1.13E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	390	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	22	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	367	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	27	n/a	n/a	7.2	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	121	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	80	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	125	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Baker's yeast)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.80E+3	n/a	n/a	n/a	n/a	7.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	12	n/a	310	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	660	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	175	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	25	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	97	n/a	n/a	7.2	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	35	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.55E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.15E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19992 (2-{3-[3-({[2-chloro-3-(trifluoromethyl)phenyl]meth...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	289	n/a	n/a	n/a	n/a
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