BDBM19993 CHEMBL62136::N-[4-(1,1,1,3,3,3-hexafluoro-2-hydroxypropan-2-yl)phenyl]-N-(2,2,2-trifluoroethyl)benzenesulfonamide::T 0901317::T0901317::TO-901317::US10543183, Compound TO901317::US10669296, Compound TO901317::US10945978, Compound 1::[3H]T0901317

SMILES: c1ccc(cc1)S(=O)(=O)[N@@](CC(F)(F)F)c2ccc(cc2)C(C(F)(F)F)(C(F)(F)F)O

InChI Key: InChIKey=SGIWFELWJPNFDH-UHFFFAOYSA-N

Data: 6 KI  62 IC50  2 Kd  114 EC50

PDB links: 9 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 179 hits for monomerid = 19993   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha [197-447] (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	16	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	55	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	30	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	60	n/a	n/a	7.5	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	40	n/a	13	n/a	n/a	8.0	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Alpha-glucosidase MAL32 (Baker's yeast)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+5	n/a	n/a	n/a	n/a	7.0	37
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	170	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	140	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	40	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	16	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	20	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	800	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	940	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	359	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	333	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	198	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	8	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	6	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	21	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor ROR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	120	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Presenilin-1 (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	3.60E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Presenilin-1 (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Presenilin-1 (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	190	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Rat)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	530	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor ROR-gamma (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	330	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor ROR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Bile acid receptor (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	15	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	50	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	10	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha/Retinoic acid receptor RXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.0980	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta/Retinoic acid receptor RXR-alpha (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	0.108	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Nuclear receptor subfamily 1 group I member 2 (Human)	BDBM19993 (CHEMBL62136 | [3H]T0901317 | T 0901317 | N-[4-(1,1...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair