BDBM20000 2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl]phenoxymethyl}phenyl)acetic acid::CHEMBL214719::JMC496151 Compound 15::WAY-254011

SMILES: OC(=O)Cc1ccc(COc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1

InChI Key: InChIKey=VXHRQVMQVYQGQG-UHFFFAOYSA-N

Data: 12 IC50  11 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 20000   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-beta (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-alpha (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-beta (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-alpha (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-beta (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Peroxisome proliferator-activated receptor gamma (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	680	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-alpha (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	240	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	90	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-alpha [197-447] (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.5	n/a	n/a	n/a	n/a	7.4	4
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					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.5	n/a	238	n/a	n/a	n/a	n/a
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Oxysterols receptor LXR-beta [154-461] (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	93	n/a	n/a	7.4	4
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					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	71	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	10	n/a	240	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	90	n/a	n/a	7.4	4
TBA									Citation and Details
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-beta [154-461] (Human)	BDBM20000 (CHEMBL214719 | 2-(4-{3-[3-benzyl-8-(trifluoromethy...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.10	n/a	71	n/a	n/a	7.4	4
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					More data for this Ligand-Target Pair