BDBM200749 US9233108, 11::US9757383, Example 11

SMILES CN(CCCn1c2ccc(CNC[C@H](O)c3ccc(O)c4[nH]c(=O)ccc34)cc2sc1=O)[C@H]1CC[C@@H](CC1)OC(=O)C(O)(c1cccs1)c1cccs1

InChI Key InChIKey=XJHGFZGUOALOCT-LNFMTQTQSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 200749   

TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM200749(US9233108, 11 | US9757383, Example 11)
Affinity DataIC50:  4.20nMT: 2°CAssay Description:The study of binding to human adrenergic beta1 and beta2 receptors was performed using commercial membranes prepared from Sf9 cells where they are ov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM200749(US9233108, 11 | US9757383, Example 11)
Affinity DataIC50:  0.5nMAssay Description:The study of binding to human muscarinic M1, M2, M3, M4 and M5 receptors was performed using commercial membranes (Perkin Elmer) prepared from CHO-K1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBeta-2 adrenergic receptor(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM200749(US9233108, 11 | US9757383, Example 11)
Affinity DataIC50:  4.20nMAssay Description:The study of binding to human adrenergic beta1 and beta2 receptors was performed using commercial membranes prepared from Sf9 cells where they are ov...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
Almirall

US Patent
LigandPNGBDBM200749(US9233108, 11 | US9757383, Example 11)
Affinity DataIC50:  0.5nMAssay Description:The study of binding to human muscarinic M1, M2, M3, M4 and M5 receptors was performed using commercial membranes (Perkin Elmer) prepared from CHO-K1...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent