BDBM200835 US9233111, 38

SMILES CC(C)(C)c1ccc(cc1)C(=O)Nc1cccc(c1CO)-c1ncnc2[nH]c(cc12)C1=CCN(CC1)C(=O)CF

InChI Key InChIKey=WTMWKOGRGZGVBZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 200835   

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM200835(US9233111, 38)
Affinity DataIC50: 20nMT: 2°CAssay Description:Alternatively, the present compounds might also be assessed for their capacity to inhibit Btk-dependent FcG receptor-induced IL-8 secretion in human ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
US Patent

TargetTyrosine-protein kinase BTK(Human)
Novartis

US Patent
LigandPNGBDBM200835(US9233111, 38)
Affinity DataIC50: 27nMpH: 7.5 T: 2°CAssay Description:The inhibitory activity of the present compounds against Btk was assessed in a biochemical enzyme assay. Assay plates in 384 well format were prepare...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/14/2016
Entry Details
US Patent