BindingDB logo
myBDB logout

BDBM200845 US9533999, i-6

SMILES: FC(F)(F)c1ccccc1CCN1C(=O)CS(=O)(=O)c2cccnc12

InChI Key: InChIKey=FQUVGUORVFVGAA-UHFFFAOYSA-N

Data: 1 IC50

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 200845   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Intermediate conductance calcium-activated potassium channel protein 4


(Homo sapiens (Human))
BDBM200845
PNG
(US9533999, i-6)
Show SMILES FC(F)(F)c1ccccc1CCN1C(=O)CS(=O)(=O)c2cccnc12
Show InChI InChI=1S/C16H13F3N2O3S/c17-16(18,19)12-5-2-1-4-11(12)7-9-21-14(22)10-25(23,24)13-6-3-8-20-15(13)21/h1-6,8H,7,9-10H2
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
PC cid
PC sid
UniChem
US Patent
n/an/a 5.00E+3n/an/an/an/an/an/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
HEK293 cells over-expressing human KCa3.1 are used to measure the effects of compounds in inhibiting the KCa3.1 channel function. The assay is based ...


US Patent US9533999 (2017)


BindingDB Entry DOI: 10.7270/Q21V5C4S
More data for this
Ligand-Target Pair