BDBM20244 4-[(2S)-2-{[(1S)-1-{[(1S)-5-amino-1-{[(1S,2R)-1-{[(1S)-5-amino-1-{[(1S)-1-carbamoyl-2-phenylethyl]carbamoyl}pentyl]carbamoyl}-2-hydroxypropyl]carbamoyl}pentyl]carbamoyl}-3-methylbutyl]carbamoyl}-2-acetamidoethyl]phenoxyphosphonic acid::BMCL13633 Stat3 (705) derived peptide, 1::acetyl-pYLKTKF-amide, 1

SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(OP(O)(O)=O)cc1)NC(C)=O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](C(C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](Cc1ccccc1)C(N)=O

InChI Key InChIKey=CYNUMKMAGUXQME-RLADWIAXSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20244   

TargetSignal transducer and activator of transcription 3 [127-722](Mus musculus (mouse))
University Of Michigan

LigandPNGBDBM20244(4-[(2S)-2-{[(1S)-1-{[(1S)-5-amino-1-{[(1S,2R)-1-{[...)
Affinity DataKi:  2.59E+4nM ΔG°:  -6.19kcal/molepH: 7.5 T: 2°CAssay Description:Fluorescence polarization (FP) binding assay is utilizing the intrinsic property of the fluorescent probe, which will have low polarization value whe...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSignal transducer and activator of transcription 3(Mus musculus (mouse))
The University Of Texas At Houston

LigandPNGBDBM20244(4-[(2S)-2-{[(1S)-1-{[(1S)-5-amino-1-{[(1S,2R)-1-{[...)
Affinity DataIC50:  2.00E+4nMpH: 7.8 T: 2°CAssay Description:His10-Stat3 was expressed in Sf9 cells from a baculovirus encoding the recombinant protein. A nuclear extract of the Sf9 cells was incubated with 32P...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed