BDBM20284 CHEMBL391997::CPZ::Capsazepine::N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-1,3,4,5-tetrahydro-2-benzazepine-2-carbothioamide::N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-tetrahydro-1H-2-benzazepine-2-carbothioamide

SMILES: c1cc(ccc1CCNC(=S)N2CCCc3cc(c(cc3C2)O)O)Cl

InChI Key: InChIKey=DRCMAZOSEIMCHM-UHFFFAOYSA-N

Data: 15 KI  34 IC50  6 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 52 hits for monomerid = 20284   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	220	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	334	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	590	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	320	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	69	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	887	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	6.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.51E+3	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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Transient receptor potential cation channel subfamily M member 8 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	1.80E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Mouse)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Mouse)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	150	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	68	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Mouse)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily M member 8 (Mouse)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	420	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	32	n/a	n/a	7.2	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1/2/4 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	>1.00E+5	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	365	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		120	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		520	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.29E+3	-8.03	n/a	n/a	282	n/a	n/a	7.4	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30E+3	-8.35	n/a	n/a	520	n/a	n/a	7.4	37
TBA									Citation and Details
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Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20284 (N-[2-(4-chlorophenyl)ethyl]-7,8-dihydroxy-2,3,4,5-...) Show SMILES Show InChI	GoogleScholar	UniChem		1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
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