BDBM20334 1-Isoquinolin-5-yl-3-(4-trifluoromethyl-benzyl)-urea::1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]methyl}urea::A-425619::CHEMBL104028::JMC48744 Compound 14a

SMILES: FC(F)(F)c1ccc(CNC(=O)Nc2cccc3cnccc23)cc1

InChI Key: InChIKey=SJGVXVZUSQLLJB-UHFFFAOYSA-N

Data: 3 KI  6 IC50  5 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 15 hits for monomerid = 20334   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	2.10	n/a	n/a	7.4	22
TBA									Citation and Details
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Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	4	n/a	n/a	7.4	22
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Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	n/a	n/a	24	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		18	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20334 (1-isoquinolin-5-yl-3-{[4-(trifluoromethyl)phenyl]m...) Show SMILES Show InChI	GoogleScholar	UniChem		47	-9.99	n/a	n/a	11	n/a	n/a	7.4	25
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					More data for this Ligand-Target Pair