BDBM20383 1-isoquinolin-5-yl-3-{1-[4-(trifluoromethyl)phenyl]ethyl}urea::CHEMBL389715::isoquinoline antagonist, 5a

SMILES CC(NC(=O)Nc1cccc2cnccc12)c1ccc(cc1)C(F)(F)F

InChI Key InChIKey=FIRXVLDQHKDDGB-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 20383   

TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM20383(1-isoquinolin-5-yl-3-{1-[4-(trifluoromethyl)phenyl...)
Affinity DataIC50:  22nMAssay Description:Blockade of human TRPV1 receptor assessed as inhibition of capsaicin-induced calcium fluxMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Homo sapiens (Human))
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM20383(1-isoquinolin-5-yl-3-{1-[4-(trifluoromethyl)phenyl...)
Affinity DataEC50:  22nMpH: 7.4 T: 2°CAssay Description:The functional antagonist activity of compounds at the TRPV1 receptor was determined with a Ca2+ influx assay by measuring the effect on capsaicin (0...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed