BDBM204261 US9242996, 335

SMILES Nc1ncc(nc1-c1ccc(C(=O)N[C@H](CO)c2cc(F)cc(c2)C(F)F)c(F)c1)C1CCOCC1

InChI Key InChIKey=VBWIWPHRVDDGOJ-OAQYLSRUSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 204261   

TargetMitogen-activated protein kinase 1(Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM204261(US9242996, 335)
Affinity DataIC50:  0.0208nMpH: 7.5Assay Description:Compound potency against activated ERK2 was determined using a kinase assay that measures ERK2-catalyzed phosphorylation of biotinylated ERKtide pept...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent