Molecular Structure for 20464

AMG6880 (2E)-3-[2-(piperidin-1-yl)-6-(trifluoromethyl)pyridin-3-yl]-N-(quinolin-7-yl)prop-2-enamide

Data: 1 KI 2 IC50 1 EC50

Vconf -m prep

Found 3 hits in this search
Target (Institution)	Ligand	Target Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	pH	Temp °C
Vanilloid Receptor 1 (TRPV1, VR1) Homo sapiens (human)	AMG6880 ((2E)-3-[2-(piperidin-1-yl)-6-(trifluoromethyl)pyri...)	DrugBank GoogleScholar KEGG MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS PC cid PC sid	PubMed	27.000	-43.199	n/a	n/a	34.0	7.4	25
Abbott Laboratories			CHEBI CSLS PC cid PC sid	PubMed	J Pharmacol Exp Ther. 323: 285-93 (2007)
Vanilloid Receptor 1 (TRPV1, VR1) Homo sapiens	AMG6880 ((2E)-3-[2-(piperidin-1-yl)-6-(trifluoromethyl)pyri...)	DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS PC cid PC sid	PubMed	n/a	n/a	0.42	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL			CHEBI CSLS PC cid PC sid	PubMed	J Med Chem. 48: 71-90 (2005)
Vanilloid Receptor 1 (TRPV1, VR1) Homo sapiens	AMG6880 ((2E)-3-[2-(piperidin-1-yl)-6-(trifluoromethyl)pyri...)	DrugBank GoogleScholar MMDB PDB UniProtKB/SwissProt UniProtKB/TrEMBL	CHEBI CSLS PC cid PC sid	PubMed	n/a	n/a	1.0	n/a	n/a	n/a	n/a
Amgen Inc. Curated by ChEMBL			CHEBI CSLS PC cid PC sid	PubMed	J Med Chem. 48: 71-90 (2005)