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BDBM205058 US9556132, 22::process for preparing 1-(2-fluorophenyl)-5-{2-[2-(trifluoromethyl)phenyl]phenyl}-1h-1,2,3,4-tetrazole

SMILES: Fc1ccccc1-n1nnnc1-c1ccccc1-c1ccccc1C(F)(F)F

InChI Key: InChIKey=LHPBFPDNZHNCNV-UHFFFAOYSA-N

Data: 1 IC50

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   Substructure
Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 205058   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Intermediate conductance calcium-activated potassium channel protein 4


(Homo sapiens (Human))
BDBM205058
PNG
(US9556132, 22 | process for preparing 1-(2-fluorop...)
Show SMILES Fc1ccccc1-n1nnnc1-c1ccccc1-c1ccccc1C(F)(F)F
Show InChI InChI=1S/C20H12F4N4/c21-17-11-5-6-12-18(17)28-19(25-26-27-28)15-9-2-1-7-13(15)14-8-3-4-10-16(14)20(22,23)24/h1-12H
PDB

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KEGG

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DrugBank
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PC cid
PC sid
UniChem
US Patent
n/an/a 1.70E+3n/an/an/an/a7.3n/a



Saniona A/S

US Patent


Assay Description
Human HEK293 cells over-expressing human IK are grown in culture medium (DMEM supplemented with 10% foetal bovine serum), in polystyrene culture flas...


US Patent US9556132 (2017)


BindingDB Entry DOI: 10.7270/Q2SF2Z5T
More data for this
Ligand-Target Pair