BDBM205088 US9556145, example 8::methyl 3-fluoro-2-{[(3r,6r)-6- methyl-1-{[2-(2h-1,2,3-triazol- 2-yl)phenyl]carbonyl}piperidin- 3-yl]oxy}pyridine-4-carboxylate

SMILES COC(=O)c1ccnc(O[C@@H]2CC[C@@H](C)N(C2)C(=O)c2ccccc2-n2nccn2)c1F

InChI Key InChIKey=LZLYXFISYCWTSC-HUUCEWRRSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 205088   

TargetOrexin/Hypocretin receptor type 1(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM205088(US9556145, example 8 | methyl 3-fluoro-2-{[(3r,6r)...)
Affinity DataIC50:  1.69E+3nMAssay Description:TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetOrexin receptor type 2(Homo sapiens (Human))
Merck Sharp & Dohme

US Patent
LigandPNGBDBM205088(US9556145, example 8 | methyl 3-fluoro-2-{[(3r,6r)...)
Affinity DataIC50:  24.9nMAssay Description:TBDIn a typical experiment the OX1 and OX2 receptor antagonistic activity of the compounds of the present invention was determined in accordance with...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent