BDBM205182 3-methyl-2-({(3r,6r)-6- methyl-1-[(3-pyrimidin-2- ylthiophen-2- yl)carbonyl]piperidin-3- yl}oxy)pyridine-4- carbonitrile::US9546152, example 75
SMILES C[C@@H]1CC[C@H](CN1C(=O)c1sccc1-c1ncccn1)Oc1nccc(C#N)c1C
InChI Key InChIKey=IGGMQLWKZGOINS-RHSMWYFYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 205182
Affinity DataKi: 0.800nMAssay Description:Radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430) in which the inhibition constant (Ki) is determ...More data for this Ligand-Target Pair
Affinity DataKi: 386nMAssay Description:Radioligand binding assay (described in Bergman et. al. Bioorg. Med. Chem. Lett. 2008, 18, 1425-1430) in which the inhibition constant (Ki) is determ...More data for this Ligand-Target Pair
Affinity DataIC50: 15nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:The utility of the compounds in accordance with the present invention as orexin receptor OX1R and/or OX2R antagonists may be readily determined witho...More data for this Ligand-Target Pair