BDBM20557 AMG 517::CHEMBL229430::JMC503515 Compound 23::N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl}oxy)-1,3-benzothiazol-2-yl]acetamide::US8796328, A::US8802711, H

SMILES: CC(=O)Nc1nc2c(Oc3cc(ncn3)-c3ccc(cc3)C(F)(F)F)cccc2s1

InChI Key: InChIKey=YUTIXVXZQIQWGY-UHFFFAOYSA-N

Data: 22 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 22 hits for monomerid = 20557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
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Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.760	n/a	n/a	n/a	n/a	n/a	n/a
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					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	5.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	5.0	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.900	n/a	n/a	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.760	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Human)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.620	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Transient receptor potential cation channel subfamily V member 1 (Rat)	BDBM20557 (N-[4-({6-[4-(trifluoromethyl)phenyl]pyrimidin-4-yl...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair