BDBM20586 2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,2,3,4-tetrahydroisoquinolin-6-ol::tetrahydroisoquinoline derivative, 18a

SMILES: c1ccc(cc1)N2CCc3cc(ccc3[C@H]2c4ccc(cc4)OCCN5CCCCC5)O

InChI Key: InChIKey=FMWVCTJKLAVRPB-UHFFFAOYSA-N

Data: 8 IC50  4 EC50

PDB links: 1 PDB ID matches this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 20586   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Human)	BDBM20586 (2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	16.5	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM20586 (2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	346	n/a	289	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM20586 (2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19	n/a	16.5	n/a	n/a	7.4	22
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM20586 (2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	346	n/a	289	n/a	n/a	n/a	25
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM20586 (2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	16.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM20586 (2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	346	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor (Human)	BDBM20586 (2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	19.0	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Estrogen receptor beta (Human)	BDBM20586 (2-phenyl-1-{4-[2-(piperidin-1-yl)ethoxy]phenyl}-1,...) Show SMILES Show InChI	GoogleScholar	UniChem		n/a	n/a	289	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair