BDBM205995 US9255098, Ex. 1::US9255098, Ex. 4

SMILES CC#CCn1c(nc2n(C)c(=O)n(Cc3nc4cc(F)ccc4s3)c(=O)c12)N1CCC[C@@H](N)C1

InChI Key InChIKey=KNVUDUILISDHBC-OAHLLOKOSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 205995   

TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Chengdu Easton Pharmaceutical

US Patent
LigandPNGBDBM205995(US9255098, Ex. 1 | US9255098, Ex. 4)
Affinity DataIC50:  0.0800nMT: 2°CAssay Description:Gly-Pro-7-amido-4-methylcoumarin can be hydrolyzed by dipeptidyl peptidase IV (DPP-IV) at room temperature, to generate 7-amido-4-methyl coumarin, wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetDipeptidyl peptidase 4(Homo sapiens (Human))
Chengdu Easton Pharmaceutical

US Patent
LigandPNGBDBM205995(US9255098, Ex. 1 | US9255098, Ex. 4)
Affinity DataIC50:  0.0500nMT: 2°CAssay Description:Gly-Pro-7-amido-4-methylcoumarin can be hydrolyzed by dipeptidyl peptidase IV (DPP-IV) at room temperature, to generate 7-amido-4-methyl coumarin, wh...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent